SPHK2 Human shRNA Plasmid Kit (Locus ID 56848)
Specifications
| Product Data | |
| Locus ID | 56848 |
|---|---|
| Synonyms | SK-2; SK 2; SPK-2; SPK 2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | SPHK2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 56848). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001204158, NM_001204159, NM_001204160, NM_001243876, NM_020126, NM_020126.1, NM_020126.2, NM_020126.3, NM_020126.4, NM_001243876.1, NM_001204158.1, NM_001204158.2, NM_001204160.1, NM_001204160.2, NM_001204159.1, NM_001204159.2, BC006161, BC006161.1, BC010671, NM_001204158.3, NM_020126.5, NM_001204160.3, NM_001204159.3 |
| UniProt ID | Q9NRA0 |
| Summary | This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Aug 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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