EVER2 (TMC8) Human shRNA Plasmid Kit (Locus ID 147138)
Specifications
| Product Data | |
| Locus ID | 147138 |
|---|---|
| Synonyms | EV2; EVER2; EVIN2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | TMC8 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 147138). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_152468, NM_152468.1, NM_152468.2, NM_152468.3, NM_152468.4, BC110296, BC110296.1, BC028076, BC141865, NM_152468.5 |
| UniProt ID | Q8IU68 |
| Summary | Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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