VEPH1 Human shRNA Plasmid Kit (Locus ID 79674)
Specifications
| Product Data | |
| Locus ID | 79674 |
|---|---|
| Synonyms | MELT; VEPH |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | VEPH1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 79674). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001167911, NM_001167912, NM_001167915, NM_001167916, NM_001167917, NM_024621, NM_024621.1, NM_024621.2, NM_001167917.1, NM_001167915.1, NM_001167916.1, NM_001167911.1, NM_001167912.1, BC101660, BC101660.1, BC111017, BC026235, BC042159, BC057999, BC078142, BC113555, NM_001167915.2, NM_001167916.2, NM_001167912.2, NM_001167911.2 |
| UniProt ID | Q14D04 |
| Summary | Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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