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WNT5B Human shRNA Plasmid Kit (Locus ID 81029)

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SKU
TR300445
WNT5B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 81029
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components WNT5B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 81029). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_030775, NM_032642, NM_030775.1, NM_030775.2, NM_032642.1, NM_032642.2, BC001749, BC001749.1, NM_032642.3
UniProt ID Q9H1J7
Summary The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer
Tentler, Nallapareddy, Tan et al
Mol Cancer Ther (2010) 9 (12), 3351-62 DOI: 10.1158/1535-7163.MCT-10-0376
AI Summary: OriGene products, specifically Wnt pathway shRNA constructs, were used for gene knockdown experiments to demonstrate that Wnt signaling contributes to resistance to the MEK1/2 inhibitor AZD6244 in K-ras-mutated colorectal cancer cell lines.
FigureFigure
Showing 1-1 of 1 papers.
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