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Positive shRNA control against eGFP (pRS Vector)

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SKU
TR30001
HuSH 29-mer shRNA against eGFP (in pRS Vector), 5 ug
  $270.00
In Stock*
Specifications
Specifications
Product Data
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store the vector DNA at -20°C.
Stability Vector DNA is stable for at least one year from date of receipt when stored at -20°C.
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Documents
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file-alt Citations

Significance of cortactin as a prognostic factor in biliary cancer and its relevant signaling pathways as a therapeutic target
조연아
Thesis (2021)
Snippet: Biliary tract carcinomas are rare, accounting for less than 1% of all cancers. However, their incidence has recently increased in Japan and industrialized countries, such as the USA. Particularly, in Korea, biliary tract carcinomas are common, ranking 9th in and . Its , Save;CTTN shRNA was used for lentiviral transduction (ORIGENE TR30001, 5′- CACAAGCTGGAGTACAACTACAACAGCCA-3′)
The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability
Dilworth, Gudavicius, Xu et al
Nucleic Acids Res. (2018) 46 (5), 2459-2478 DOI: 10.1093/nar/gky008
AI Summary: OriGene’s HuSH 29-mer shRNA expression vectors were used to generate FKBP25 knockdown U2OS cell lines, enabling the study of FKBP25’s role in microtubule polymerization and cell cycle regulation.
Snippet: table U2OS shRNA knockdown cells were generated by transfection with HuSH 29-mer shRNA expression vectors (Origene, Rockville, MD, USA) using GenJet U2OS Transfection Reagent (SignaGen, Rockville, MD, USA) followed by selection with puromycin (InvivoGen, San Diego, CA, USA) 48 h post-transfection until colonies formed
FigureFigureFigure
Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a
Spinelli, Fusco, Mainardi et al
Nat Commun (2017) 8 (1), 2009 DOI: 10.1038/s41467-017-02221-9
AI Summary: OriGene products contributed to this study by providing plasmids encoding control shRNA, zDHHC3 shRNA, and EGFP, which were used to manipulate gene expression and investigate the molecular mechanisms underlying hippocampal synaptic plasticity and memory impairment.
Snippet: Plasmid-encoding for control shRNA, zDHHC3 shRNA, and EGFP were from Origene. Plasmid-encoding for GluA1 WT and GluA1 C585S/C811S were a gift from Prof. Richard L. Huganir (The Johns Hopkins University, Baltimore, MD)
FigureFigureFigure
Autoantibody responses to nodal and paranodal antigens in chronic inflammatory neuropathies
Mathey, Garg, Park et al
J Neuroimmunol (2017) 309, 41-46 DOI: 10.1016/j.jneuroim.2017.05.002
Cited by 56
AI Summary: OriGene products, specifically human neurofascin 155, contactin-1, and neurofascin 186 proteins, were used as antigens in ELISA assays to detect autoantibodies in patient sera, facilitating the identification of specific immune responses in chronic inflammatory neuropathies.
The insulin-like growth factor I receptor regulates glucose transport by astrocytes
Hernandez-Garzón, Fernandez, Perez-Alvarez et al
Glia (2016)
Cited by 73
AI Summary: OriGene products, specifically HuSH-29 shRNAs targeting Glut-1, IGF-IR, IR, scramble sequence, and EGFP, were used to selectively knock down these genes and investigate their roles in astrocytic glucose transport in this study.
Snippet: shRNAs against Glut-1, IGF-IR, IR, scramble sequence and EGFP were from Origene (HuSH-29, Origene, USA): shRNA against GIPC was constructed as described in www.addgene.org/tools/protocols/plko/using the primers: 5 ... Cite SaveSaving
The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis
Bonuccelli, Castello-Cros, Capozza et al
Cell Cycle (2012) 11 (21), 3972-82 DOI: 10.4161/cc.22227
Cited by 42
AI Summary: OriGene products, specifically the human cDNA of GFP-tagged casein α s1 (RG220806) and the empty vector pCMV6-AC-GFP (PS100010), were used to generate and control the expression of α-casein in mammary tumor cells, enabling the study of its tumor-suppressive effects in this research.
Snippet: For example, increased activation of STAT1 (via its phosphorylation) is associated with a good prognosis in human breast cancer patients, 15 with ... human cDNA of GFP tagged-casein α s1 (RG220806) and the empty vector pCMV6-AC-GFP (PS100010) were from Origene.
Showing 1-6 of 8 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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