Mir146a Mouse MicroRNA Expression Plasmid (MI0000170)

SKU
SC400782
Expression plasmid for mouse microRNA Mir146a
  $424.00
In Stock*
Specifications
Specifications
Product Data
Species Mouse
Vector pCMV-MIR
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequences
Precursor: AGCUCUGAGAACUGAAUUCCAUGGGUUAUAUCAAUGUCAGACCUGUGAAAUUCAGUUCUUCAGCU:
Mature Sequence: UGAGAACUGAAUUCCAUGGGUU:
Full Insert
>MI0000170 AGCAGTCCTCTTGATGCACCTTCTTCTTCGCTGGGATTATGGGGTGGCCTCAAACTGACATTTCTCCTGC
TGCAGGCTCATGAATGTTGAGATTACAGGCTTGCACCACATGCCCAGCATGTTTAATGATTGCTTATGAA
CTTGCCTATCTTGTGTCCCAGATCCTTATGCATCAAGAGTGTCCAGTCTGCAGAGGCCGTGCTTTTGGAT
TTATCAGAGATTTCTCTTGTGTTTTTACAGGGCTGGCAGGATCTGGCCTGGGAGGAAGGCCTCATCTGGA
GAGTCTGTGTGTATCCCCAGCTCTGAGAACTGAATTCCATGGGTTATATCAATGTCAGACCTGTGAAATT
CAGTTCTTCAGCTGGGATAGCTCTGTCATCACGGACCTGAAGAACACTGGTTGGAACAAACTCTGAAGGC
CTTCATAGTCTGCCAAGGAACTTGAAGAGTGGAGAGAGTGGGGTGAAGCGTGGAACTGCTGGCACCGGAG
GGAGTCATGTTGGATTGATGTGTGTTCTAATTTCATTTCTGTTGCTCTGATAAAATATCTTGACAAAAAC
AATTTAGGGGAGAAAGGGTTTATTAGATTATAATTCCAGGTCACAGCTGATCATTATAGGGAAGACAAAG
TAGGAACTTGAAGCAGCTCGTCTCAT
Components 1 x 10 ug vial miRNA plasmid lyophilized in a 2-D bar-coded Matrix tube
Also Contains Both mature and minor (star) miRNA can be over expressed from the construct.
OTI Disclaimer All miRNA clones were sequenced to ensure that the pre-mir sequences match reference sequence in miRBase. The flanking sequence of a miRNA clone may differ from the NCBI reference with respect to biological polymorphisms. This should not affect the function of the mature miRNA.
Shipping Ambient
Reference Data
RefSeq MI0000170
Synonyms Mirn146 mmu-mir-146
Locus ID 387164
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Documents
Resources

file-alt Citations

ICAM-1-decorated extracellular vesicles loaded with miR-146a and Glut1 drive immunomodulation and hinder tumor progression in a murine model of breast cancer
Duarte-Sanmiguel, Salazar-Puerta, Panic et al
Biomater Sci (2023)
Cited by 26
AI Summary: In this study, OriGene products—including the pCMV6-entry tagged cloning vector (PS100001), pCMV6-entry ICAM-1-mouse (MG227081), pCMV6-entry SLC2a1 (MR207871), and pCMV6-entry miR-146a mouse MicroRNA expression plasmid (SC400782)—were used to engineer extracellular vesicles for targeted immunomodulation and inhibition of tumor progression in a murine breast cancer model.
Snippet: … Myeloid-derived suppressor cells (MDSCs), for example, are immature innate immune cells that Save;pCMV6-entry tagged cloning vector Origene PS100001 N/A Myc-DDK pCMV6-entry ICAM-1-mouse intracellular adhesion molecule-1 Origene MG227081 Mouse Tagged ORF clone Myc-DDK pCMV6-entry SLC2a1 mouse solute carrier family 2 (facilitated glucose transporter Origene MR207871 Mouse Tagged ORF clone Myc-DDK pCMV6-entry miR-146a mouse MicroRNA expression plasmid Origene SC400782 N/A N/A pCMV-MIR
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