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MIR506 Human MicroRNA Expression Plasmid (MI0003193)

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SKU
SC400433
Expression plasmid for human microRNA MIR506
  $424.00
In Stock*

Frequently Bought Together (1)

CC100003 DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
5 x 200 ul
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Specifications
Specifications
Product Data
Species Human
Vector pCMV-MIR
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequences
Precursor: GCCACCACCAUCAGCCAUACUAUGUGUAGUGCCUUAUUCAGGAAGGUGUUACUUAAUAGAUUAAUAUUUGUAAGGCACCCUUCUGAGUAGAGUAAUGUGCAACAUGGACAACAUUUGUGGUGGC:
Mature Sequence: UAAGGCACCCUUCUGAGUAGA:
Full Insert
>MI0003193 GGATTCTGACTGAAATGGCGGAGTGAGGGACATTTTCCGCTGTGCTGTGTGTAGTGCTTCACTTCAAGAA
GTGCCATGCATGTGTCTAGAAATATGTTTTGCACCTTTTGGAGTGAAATAATGCACAACAGATACAAGTC
AGAACTACCCACTCAGTGATGGGTCAACTCATACAACCCTTTAAAGAGAATTCTGTGGGGTAAAACCTAG
AGGATGAGGTTCTCTGGGAATAGCCTCATCTGTAGTTTCCCCGTGTTACTATTAAGATGGTCAGTGCCAC
CACCATCAGCCATACTATGTGTAGTGCCTTATTCAGGAAGGTGTTACTTAATAGATTAATATTTGTAAGG
CACCCTTCTGAGTAGAGTAATGTGCAACATGGACAACATTTGTGGTGGCATTGGTAATGACGAGTGGAAT
TTCAGTGACAATACTGCCCTCCCTTGAGCCTTGGTACCCAACCTTTAGTGATGAGCCATTTCCAGGTACT
CTCTGAAGTACCTCTTGAGAGATCTGCTCCAGAATCTGAGGGTGCCTGGGAAAAGTCTCTCATGTAGGTT
TTTCAATTATTTATTGCTTTTTCTCCACAAAATGACTGACTACACTGGAAACAAGATTTGAGGTAGGAAC
ATGATACTTCTTTTTCTCTTGTACCTCTTAGTCTTTTCTCTCTATAACAACCCAAATACACTTCTTGC
Components 1 x 10 ug vial miRNA plasmid lyophilized in a 2-D bar-coded Matrix tube
Also Contains Both mature and minor (star) miRNA can be over expressed from the construct.
OTI Disclaimer All miRNA clones were sequenced to ensure that the pre-mir sequences match reference sequence in miRBase. The flanking sequence of a miRNA clone may differ from the NCBI reference with respect to biological polymorphisms. This should not affect the function of the mature miRNA.
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Reference Data
RefSeq MI0003193
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Documents
Resources

file-alt Citations

Downregulation of miR-506-3p Facilitates EGFR-TKI Resistance through Induction of Sonic Hedgehog Signaling in Non-Small-Cell Lung Cancer Cell Lines
Haque, Kawsar, Motes et al
Int J Mol Sci (2020) 21 (23) DOI: 10.3390/ijms21239307
Cited by 33
AI Summary: OriGene contributed to this study by providing the pCMV-miR-506-3p vector (cat. no. SC400433), which was used to overexpress miR-506-3p in erlotinib-resistant NSCLC cells to investigate its role in reversing drug resistance.
Snippet: Erlotinib-resistant cells, HCC4006ER4,were transfected with pCMV-miR-506-3p vector or empty vector without the miR-506-3p gene (purchased from Origene, USA;cat. no. SC400433),
FigureFigureFigure
Showing 1-1 of 1 papers.
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