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MIR183 Human MicroRNA Expression Plasmid (MI0000273)

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SKU
SC400212
Expression plasmid for human microRNA MIR183
  $424.00
In Stock*

Frequently Bought Together (1)

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5 x 200 ul
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Specifications
Specifications
Product Data
Species Human
Vector pCMV-MIR
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequences
Precursor: CCGCAGAGUGUGACUCCUGUUCUGUGUAUGGCACUGGUAGAAUUCACUGUGAACAGUCUCAGUCAGUGAAUUACCGAAGGGCCAUAAACAGAGCAGAGACAGAUCCACGA:
Mature Sequence: UAUGGCACUGGUAGAAUUCACU:
Full Insert
>MI0000273 AGTCTGGGTGATGTGGAGGGATGTGGGCCTTCAGGTGGAGATAGGAGACACCTTGGTGTGGTCTTCTCCT
CTGCAAGGCCAGAAGGTCAGCTCCTCTCCCGCACTGTCCCTGTCTCCTTGAAGGTCATCTTGGGCTGATG
GGGCATGTGGATCTTGTGAAGAGGTGGGATGGGGTGGGGGGTAGAGACCGTAGCAGCCGCTGCTGAGGGC
CTGCTGGGGGGCCCCCAAGGGAGTGGGCAGGCTAGGAGCAGGGAACGGGCATCGTGGGCCGCTGGTCTCT
CCGCAGGGTCGGCAGGCCGCAGAGTGTGACTCCTGTTCTGTGTATGGCACTGGTAGAATTCACTGTGAAC
AGTCTCAGTCAGTGAATTACCGAAGGGCCATAAACAGAGCAGAGACAGATCCACGAGGGCCTCCGGAGCA
CCTTACCCACTTCTGCCTTGAGTGCTCCTAGACGTCGGAAACAGGCTGCTTCCAAGGGTGCAGGGATGCA
AGGCCCCTCGTCCAGTGTGTCCCCAGAGAGCCCGCACCAGTGCCATCTGCTTGGCCGATTTTGGCACTAG
CACATTTTTGCTTGTGTCTCTCCGCTCTGAGCAATCATGTGCAGTGCCAATATGGGAAAAGCAGGACCCG
CAGCTGCGTCCGCCTCCCCTGCATCCTTGTGTCAGGGCCCCAGCCTGCTCCTCCTCAAGG
Components 1 x 10 ug vial miRNA plasmid lyophilized in a 2-D bar-coded Matrix tube
Also Contains Both mature and minor (star) miRNA can be over expressed from the construct.
OTI Disclaimer All miRNA clones were sequenced to ensure that the pre-mir sequences match reference sequence in miRBase. The flanking sequence of a miRNA clone may differ from the NCBI reference with respect to biological polymorphisms. This should not affect the function of the mature miRNA.
Shipping Ambient
Reference Data
RefSeq MI0000273
Synonyms MIRN183 miR-183 miRNA183
Locus ID 406959
Reviews
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Documents
Resources

file-alt Citations

MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates
Hordeaux, Buza, Jeffrey et al
Sci Transl Med (2020) 12 (569) DOI: 10.1126/scitranslmed.aba9188
Cited by 179
AI Summary: OriGene's MI0000273 MIR183 human miRNA expression plasmid was used (after modification) in this study to assess miR183-mediated regulation of transgene expression, helping to demonstrate that microRNA targeting can reduce dorsal root ganglion toxicity from AAV vectors in primates.
Snippet: miR183 expression. MIR183 human miRNA expression plasmid was modified from OriGene MI0000273 vector by deleting the Kpn I–Pst I fragment–encoding GFP and partial internal ribosome entry sites. …
Showing 1-1 of 1 papers.
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