IRE1 (ERN2) (NM_033266) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | N-GST and C-HIS |
| Predicted MW | 135.2 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_150296 |
| Locus ID | 10595 |
| UniProt ID | Q76MJ5 A5YM46 A5YM65 |
| Cytogenetics | 16p12.2 |
| RefSeq Size | 3549 |
| RefSeq ORF | 2922 |
| Synonyms | hIRE2p; IRE1-BETA; IRE1b; IRE2p |
| Summary | Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.UniProtKB/Swiss-Prot Function |
| Protein Categories | Enzyme: Kinases, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Protein Kinase |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "IRE1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC409637 | Lyophilized ERN2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY409637 | Transient overexpression lysate of endoplasmic reticulum to nucleus signaling 2 (ERN2) (as WB positive control) | 100 ug |
$665.00
|
|
| TP762373 | Purified recombinant protein of Human endoplasmic reticulum to nucleus signaling 2 (ERN2), Asp320-Asp617, with N-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$260.00
|
|
Citations
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