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SMAD3 (NM_005902) Human Recombinant Protein

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SKU
TP762386
Purified recombinant protein of Human SMAD family member 3 (SMAD3), transcript variant 1, Ser2-Ala230, with N-terminal His tag, expressed in E.coli, 50ug
Size:
50 ug
  $260.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region (Ser2-Ala230) of SMAD3
Tag N-His
Predicted MW 26.0 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity >80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_005893
Locus ID 4088
UniProt ID P84022
Cytogenetics 15q22.33
RefSeq Size 6256
RefSeq ORF 1275
Synonyms HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3
Summary The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. It also functions as a tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. provided by RefSeq, Nov 2019
Protein Categories Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors
Protein Pathways Adherens junction, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Pancreatic cancer, Pathways in cancer, TGF-beta signaling pathway, Wnt signaling pathway
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Other "SMAD3" proteins (6)
SKU Description Size Price
PH308749 SMAD3 MS Standard C13 and N15-labeled recombinant protein (NP_005893) 10 ug
$3,360.00
LC401784 Lyophilized SMAD3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC428691 Lyophilized SMAD3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401784 Transient overexpression lysate of SMAD family member 3 (SMAD3), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY428691 Transient overexpression lysate of SMAD family member 3 (SMAD3), transcript variant 3 (as WB positive control) 100 ug
$436.00
TP308749 Recombinant protein of human SMAD family member 3 (SMAD3), transcript variant 1, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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