GTF3A (NM_002097) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | N-GST |
| Predicted MW | 69.5 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | >80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002088 |
| Locus ID | 2971 |
| UniProt ID | Q92664 |
| Cytogenetics | 13q12.2 |
| RefSeq Size | 1404 |
| RefSeq ORF | 1095 |
| Synonyms | AP2; TFIIIA |
| Summary | The product of this gene is a zinc finger protein with nine Cis2-His2 zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins, Transciption Factors |
| Protein Families | Transcription Factors |
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Citations
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