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TTF1 (NKX2-1) (NM_003317) Human Recombinant Protein

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SKU
TP762355
Purified recombinant protein of Human NK2 homeobox 1 (NKX2-1), transcript variant 2, Gly89-Pro123-GGGGS-Leu156-His193, with N-terminal His tag, expressed in E.coli, 50ug
Size:
50 ug
  $260.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Gly89-Pro123-GGGGS-Leu156-His193) of TTF1
Tag N-His
Predicted MW 8.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_003308
Locus ID 7080
UniProt ID P43699
Cytogenetics 14q13.3
RefSeq Size 2352
RefSeq ORF 1113
Synonyms BCH; BHC; NK-2; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; TITF1; TTF-1; TTF1
Summary This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. provided by RefSeq, Feb 2014
Protein Categories Cancer: Endocrine, Endocrine and metabolic diseases, Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
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Other "TTF1" proteins (5)
SKU Description Size Price
LC401141 Lyophilized NKX2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC421530 Lyophilized NKX2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401141 Transient overexpression lysate of NK2 homeobox 1 (NKX2-1), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY421530 Transient overexpression lysate of NK2 homeobox 1 (NKX2-1), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP762371 Purified recombinant protein of Human NK2 homeobox 1 (NKX2-1), transcript variant 2, Met1-Pro123, with N-terminal His tag, expressed in E.coli, 50ug 50 ug
$260.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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