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DVL1 (NM_004421) Human Recombinant Protein

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SKU
TP762283
Purified recombinant protein of Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), Met1-Tyr279, with N-terminal His tag, expressed in E.coli, 50ug
Size:
50 ug
  $260.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Met1-Tyr279) of DVL1
Tag N-His
Predicted MW 31.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_004412
Locus ID 1855
UniProt ID O14640
Cytogenetics 1p36.33
RefSeq Size 2941
RefSeq ORF 2010
Synonyms DRS2; DVL; DVL1L1; DVL1P1
Summary DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS
Protein Pathways Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway
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Other "DVL1" proteins (4)
SKU Description Size Price
LC401404 Lyophilized DVL1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC405356 Lyophilized DVL1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401404 Transient overexpression lysate of dishevelled, dsh homolog 1 (Drosophila) (DVL1) (as WB positive control) 100 ug
$665.00
LY405356 Transient overexpression lysate of dishevelled, dsh homolog 1 (Drosophila) (DVL1), transcript variant 3 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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