RAD51C (NM_058216) Human Recombinant Protein

SKU
TP762205
Purified recombinant protein of Human RAD51 homolog C (S. cerevisiae) (RAD51C), transcript variant 1, Ala184-End, with N-terminal His tag, expressed in E.coli, 50ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Ala184-End) of RAD51C
Tag N-His
Predicted MW 22.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_478123
Locus ID 5889
UniProt ID O43502
Cytogenetics 17q22
RefSeq Size 1337
RefSeq ORF 1128
Synonyms BROVCA3; FANCO; R51H3; RAD51L2
Summary This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2013
Protein Categories Cancer: Gynecologic, Cardiovascular diseases, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Homologous recombination
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Other "RAD51C" proteins (1)
SKU Description Size Price
TP760472 Purified recombinant protein of Human RAD51 homolog C (S. cerevisiae) (RAD51C), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
$270.00

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