AGO1 (NM_012199) Human Recombinant Protein

SKU
TP761918
Purified recombinant protein of Human eukaryotic translation initiation factor 2C, 1 (EIF2C1), Gln226-Cys490, with N-terminal HIS tag, expressed in E. coli, 50ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Gln226-Cys490) of EIF2C1
Tag N-His
Predicted MW 30.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_036331
Locus ID 26523
UniProt ID Q9UL18
Cytogenetics 1p34.3
RefSeq Size 7478
RefSeq ORF 2571
Synonyms EIF2C; EIF2C1; GERP95; hAgo1; Q99
Summary This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. provided by RefSeq, Nov 2015
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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Other "AGO1" proteins (3)
SKU Description Size Price
LC402163 Lyophilized AGO1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402163 Transient overexpression lysate of eukaryotic translation initiation factor 2C, 1 (EIF2C1) (as WB positive control) 100 ug
$436.00
TP762603 Purified recombinant protein of Human eukaryotic translation initiation factor 2C, 1 (EIF2C1), full length, with N-terminal GST and C-terminal His tag, expressed in E.coli, 50ug 50 ug
$270.00

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