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LATS2 (NM_014572) Human Recombinant Protein

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SKU
TP761911
Purified recombinant protein of Human LATS, large tumor suppressor, homolog 2 (Drosophila) (LATS2), Met1-Ala237, with N-terminal HIS tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Met1-Ala237) of LATS2
Tag N-His
Predicted MW 25.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_055387
Locus ID 26524
UniProt ID Q9NRM7
Cytogenetics 13q12.11
RefSeq Size 4098
RefSeq ORF 3264
Synonyms KPM
Summary This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. provided by RefSeq, Jul 2008
Protein Categories Enzyme: Kinases, Growth Factors, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
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Other "LATS2" proteins (2)
SKU Description Size Price
LC402348 Lyophilized LATS2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402348 Transient overexpression lysate of LATS, large tumor suppressor, homolog 2 (Drosophila) (LATS2) (as WB positive control) 100 ug
$665.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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