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SIAH1 (NM_003031) Human Recombinant Protein

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SKU
TP761890
Purified recombinant protein of Human seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length SIAH1
Tag N-GST and C-His
Predicted MW 58.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_003022
Locus ID 6477
UniProt ID Q8IUQ4
Cytogenetics 16q12.1
RefSeq Size 2003
RefSeq ORF 939
Synonyms BURHAS; SIAH1A
Summary This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways p53 signaling pathway, Ubiquitin mediated proteolysis, Wnt signaling pathway
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Other "SIAH1" proteins (4)
SKU Description Size Price
LC401063 Lyophilized SIAH1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423687 Lyophilized SIAH1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401063 Transient overexpression lysate of seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY423687 Transient overexpression lysate of seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 2 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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