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RIP3 (RIPK3) (NM_006871) Human Recombinant Protein

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SKU
TP761866
Purified recombinant protein of Human receptor-interacting serine-threonine kinase 3 (RIPK3), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length RIPK3
Tag N-GST and C-His
Predicted MW 84.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_006862
Locus ID 11035
UniProt ID Q9Y572
Cytogenetics 14q12
RefSeq Size 1940
RefSeq ORF 1554
Synonyms RIP3
Summary The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. provided by RefSeq, Jul 2008
Protein Categories Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Cytosolic DNA-sensing pathway
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Other "RIP3" proteins (2)
SKU Description Size Price
TP710302 Purified recombinant protein of Human receptor-interacting serine-threonine kinase 3 (RIPK3), full length, with N-terminal GST and C-terminal His tag, expressed in sf9, 20ug 20 ug
$540.00
TP710309 Purified recombinant protein of mutant (K50A) of Human receptor-interacting serine-threonine kinase 3 (RIPK3, K50A mutant), full length, with N-terminal GST and C-terminal His tag, expressed in sf9, 20ug 20 ug
$540.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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