FUT3 (NM_000149) Human Recombinant Protein

SKU
TP761843
Purified recombinant protein of Human fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length FUT3
Tag N-GST and C-His
Predicted MW 69.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000140
Locus ID 2525
UniProt ID P21217
Cytogenetics 19p13.3
RefSeq Size 2607
RefSeq ORF 1083
Synonyms CD174; FT3B; FucT-III; LE; Les
Summary The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Differences in the expression of this gene are associated with host susceptibility to viral infection. provided by RefSeq, Aug 2020
Protein Categories Intracellular Proteins, Membrane Proteins
Protein Pathways Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways
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Other "FUT3" proteins (8)
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LC420413 Lyophilized FUT3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC420415 Lyophilized FUT3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC424899 Lyophilized FUT3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY420413 Transient overexpression lysate of fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3), transcript variant 2 (as WB positive control) 100 ug
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LY420414 Transient overexpression lysate of fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3), transcript variant 3 (as WB positive control) 100 ug
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LY420415 Transient overexpression lysate of fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3), transcript variant 4 (as WB positive control) 100 ug
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LY424899 Transient overexpression lysate of fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3), transcript variant 1 (as WB positive control) 100 ug
$436.00

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