FUT3 (NM_000149) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | N-GST and C-His |
| Predicted MW | 69.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000140 |
| Locus ID | 2525 |
| UniProt ID | P21217 |
| Cytogenetics | 19p13.3 |
| RefSeq Size | 2607 |
| RefSeq ORF | 1083 |
| Synonyms | CD174; FT3B; FucT-III; LE; Les |
| Summary | The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Differences in the expression of this gene are associated with host susceptibility to viral infection. provided by RefSeq, Aug 2020 |
| Protein Categories | Intracellular Proteins, Membrane Proteins |
| Protein Pathways | Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "FUT3" proteins (8)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC420413 | Lyophilized FUT3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC420414 | Lyophilized FUT3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC420415 | Lyophilized FUT3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC424899 | Lyophilized FUT3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY420413 | Transient overexpression lysate of fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY420414 | Transient overexpression lysate of fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| LY420415 | Transient overexpression lysate of fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3), transcript variant 4 (as WB positive control) | 100 ug |
$436.00
|
|
| LY424899 | Transient overexpression lysate of fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
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