TMEM100 (NM_018286) Human Recombinant Protein

SKU
TP761766
Purified recombinant protein of Human transmembrane protein 100 (TMEM100), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length TMEM100
Tag N-GST and C-His
Predicted MW 42.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_060756
Locus ID 55273
UniProt ID Q9NV29
Cytogenetics 17q22
RefSeq Size 1771
RefSeq ORF 402
Summary Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.UniProtKB/Swiss-Prot Function
Protein Categories Membrane Proteins
Protein Families Transmembrane
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Other "TMEM100" proteins (4)
SKU Description Size Price
LC402665 Lyophilized TMEM100 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC420469 Lyophilized TMEM100 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402665 Transient overexpression lysate of transmembrane protein 100 (TMEM100), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY420469 Transient overexpression lysate of transmembrane protein 100 (TMEM100), transcript variant 1 (as WB positive control) 100 ug
$436.00

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