TMEM100 (NM_018286) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | N-GST and C-His |
| Predicted MW | 42.2 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_060756 |
| Locus ID | 55273 |
| UniProt ID | Q9NV29 |
| Cytogenetics | 17q22 |
| RefSeq Size | 1771 |
| RefSeq ORF | 402 |
| Summary | Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.UniProtKB/Swiss-Prot Function |
| Protein Categories | Membrane Proteins |
| Protein Families | Transmembrane |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "TMEM100" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC402665 | Lyophilized TMEM100 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC420469 | Lyophilized TMEM100 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY402665 | Transient overexpression lysate of transmembrane protein 100 (TMEM100), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY420469 | Transient overexpression lysate of transmembrane protein 100 (TMEM100), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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