MYH (MUTYH) (NM_001048173) Human Recombinant Protein

SKU
TP761725
Purified recombinant protein of Human mutY homolog (E. coli) (MUTYH), transcript variant gamma3, full length, with N-terminal His tag, expressed in E. coli, 50ug
  $270.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length MUTYH
Tag N-His
Predicted MW 57.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001041638
Locus ID 4595
UniProt ID Q9UIF7
Cytogenetics 1p34.1
RefSeq Size 1791
RefSeq ORF 1563
Synonyms MYH
Summary This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Apr 2017
Protein Categories Cancer: Gastrointestinal, Intracellular Proteins
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Base excision repair
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Other "MYH" proteins (12)
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LY420769 Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant gamma2 (as WB positive control) 100 ug
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LY420770 Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant gamma3 (as WB positive control) 100 ug
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LY420771 Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant beta3 (as WB positive control) 100 ug
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LY425817 Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant gamma3 (as WB positive control) 100 ug
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LY426953 Transient overexpression lysate of mutY homolog (E. coli) (MUTYH), transcript variant alpha5 (as WB positive control) 100 ug
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TP760878 Purified recombinant protein of Human mutY homolog (E. coli) (MUTYH / MYH), transcript variant alpha1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
$270.00
TP761664 Purified recombinant protein of Human mutY homolog (E. coli) (MUTYH), transcript variant beta3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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