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FBXW8 (NM_153348) Human Recombinant Protein

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SKU
TP761689
Purified recombinant protein of Human F-box and WD repeat domain containing 8 (FBXW8), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length FBXW8
Tag N-His
Predicted MW 67.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_699179
Locus ID 26259
UniProt ID Q8N3Y1
Cytogenetics 12q24.22
RefSeq Size 4871
RefSeq ORF 1794
Synonyms FBW6; FBW8; FBX29; FBXO29; FBXW6
Summary This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Ubiquitin mediated proteolysis
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Other "FBXW8" proteins (4)
SKU Description Size Price
LC407065 Lyophilized FBXW8 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC415951 Lyophilized FBXW8 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY407065 Transient overexpression lysate of F-box and WD repeat domain containing 8 (FBXW8), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY415951 Transient overexpression lysate of F-box and WD repeat domain containing 8 (FBXW8), transcript variant 2 (as WB positive control) 100 ug
$665.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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