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SETD4 (NM_001007259) Human Recombinant Protein

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SKU
TP761421
Purified recombinant protein of Human SET domain containing 4 (SETD4), transcript variant 3, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length SETD4
Tag N-GST and C-His
Predicted MW 62.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001007260
Locus ID 54093
UniProt ID Q9NVD3
Cytogenetics 21q22.12
RefSeq Size 1183
RefSeq ORF 921
Synonyms C21orf18; C21orf27
Summary Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response (PubMed:31308046). Regulates the inflammatory response by mediating mono- and dimethylation of 'Lys-4' of histone H3 (H3K4me1 and H3K4me2, respectively), leading to activate the transcription of proinflammatory cytokines IL6 and TNF-alpha (By similarity). Also involved in the regulation of stem cell quiescence by catalyzing the trimethylation of 'Lys-20' of histone H4 (H4K20me3), thereby promoting heterochromatin formation (PubMed:31308046). Involved in proliferation, migration, paracrine and myogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) (By similarity).UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
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Other "SETD4" proteins (4)
SKU Description Size Price
LC413752 Lyophilized SETD4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423476 Lyophilized SETD4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY413752 Transient overexpression lysate of SET domain containing 4 (SETD4), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY423476 Transient overexpression lysate of SET domain containing 4 (SETD4), transcript variant 3 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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