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NOL5A (NOP56) (NM_006392) Human Recombinant Protein

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SKU
TP761154
Purified recombinant protein of Human NOP56 ribonucleoprotein homolog (yeast) (NOP56), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length NOP56
Tag N-His
Predicted MW 65.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_006383
Locus ID 10528
UniProt ID O00567
Cytogenetics 20p13
RefSeq Size 2068
RefSeq ORF 1782
Synonyms NOL5A; SCA36
Summary Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. provided by RefSeq, Jul 2016
Protein Categories Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Stem cell - Pluripotency
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Other "NOL5A" proteins (3)
SKU Description Size Price
LC416675 Lyophilized NOP56 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416675 Transient overexpression lysate of NOP56 ribonucleoprotein homolog (yeast) (NOP56), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP761841 Purified recombinant protein of Human NOP56 ribonucleoprotein homolog (yeast) (NOP56), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug 50 ug
$270.00

file-alt Citations

A PRC2-independent function for EZH2 in regulating rRNA 2'-O methylation and IRES-dependent translation
Yi, Li, Meng et al
Nat Cell Biol (2021) 23 (4), 341-354 DOI: 10.1038/s41556-021-00653-6
Cited by 109
AI Summary: OriGene contributed to this study by providing all the tagged and untagged recombinant proteins used in the protein displacement and binding assays, as detailed in Supplementary Table 5.
Snippet: Then, a third protein or an untagged version of one or the other proteins was introduced to the displacement assay to affect the existing association between beads. The alpha signals reflecting the binding affinity were measured in a Tecan plate reader in AlphaLISA detection mode. All the tagged or untagged recombinant proteins used in this assay were ordered from OriGene and the corresponding don...
Showing 1-1 of 1 papers.
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