EMAP II (AIMP1) (NM_004757) Human Recombinant Protein

SKU
TP760983
Purified recombinant protein of Human aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 (AIMP1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length AIMP1
Tag N-His
Predicted MW 34.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_004748
Locus ID 9255
UniProt ID Q12904
Cytogenetics 4q24
RefSeq Size 3159
RefSeq ORF 936
Synonyms EMAP2; EMAPII; HLD3; p43; SCYE1
Summary The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. provided by RefSeq, Dec 2008
Protein Categories Cytokines, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome
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LY428078 Transient overexpression lysate of aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 (AIMP1), transcript variant 3 (as WB positive control) 100 ug
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