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CAPON (NOS1AP) (NM_014697) Human Recombinant Protein

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SKU
TP760978
Purified recombinant protein of Human nitric oxide synthase 1 (neuronal) adaptor protein (NOS1AP), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length NOS1AP
Tag N-His
Predicted MW 56 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_055512
Locus ID 9722
UniProt ID O75052
Cytogenetics 1q23.3
RefSeq Size 2891
RefSeq ORF 1512
Synonyms 6330408P19Rik; CAPON; NPHS22
Summary This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Sep 2009
Protein Categories Intracellular Proteins
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Other "CAPON" proteins (4)
SKU Description Size Price
LC402366 Lyophilized NOS1AP HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC426640 Lyophilized NOS1AP HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402366 Transient overexpression lysate of nitric oxide synthase 1 (neuronal) adaptor protein (NOS1AP), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY426640 Transient overexpression lysate of nitric oxide synthase 1 (neuronal) adaptor protein (NOS1AP), transcript variant 2 (as WB positive control) 100 ug
$436.00

file-alt Citations

Cyclic Peptides Target CAPON and Modulate Cellular Responses under Alzheimers Disease-Relevant Stress
Abdo, Yuan, Kuncewicz et al
bioRxiv (2026)
AI Summary: OriGene’s recombinant human CAPON protein (Catalog# TP760978) was used as the immobilized target for phage display screening to identify cyclic peptide ligands in this study.
Snippet: A disulfide-constrained phage-displayed cyclic peptide library based on a CX9C scaffold was used to identify ligands capable of engaging human CAPON. Recombinant human CAPON (Origene, Catalog# TP760978) was immobilized on a solid support, and the phage library was subjected to iterative rounds of biopanning against the target protein
Showing 1-1 of 1 papers.
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