SMAD5 (NM_005903) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | N-His |
| Predicted MW | 52.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_005894 |
| Locus ID | 4090 |
| UniProt ID | Q99717 |
| Cytogenetics | 5q31.1 |
| RefSeq Size | 7014 |
| RefSeq ORF | 1395 |
| Synonyms | DWFC; JV5-1; MADH5 |
| Summary | The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2014 |
| Protein Categories | Growth Factors, Intracellular Proteins, Transciption Factors |
| Protein Families | Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors |
| Protein Pathways | TGF-beta signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "SMAD5" proteins (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC416990 | Lyophilized SMAD5 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC424347 | Lyophilized SMAD5 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC424348 | Lyophilized SMAD5 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY416990 | Transient overexpression lysate of SMAD family member 5 (SMAD5), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY424347 | Transient overexpression lysate of SMAD family member 5 (SMAD5), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY424348 | Transient overexpression lysate of SMAD family member 5 (SMAD5), transcript variant 3 (as WB positive control) | 100 ug |
$665.00
|
|
Citations
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