Wilms Tumor Protein (WT1) (NM_024424) Human Recombinant Protein

SKU
TP760644
Purified recombinant protein of Human Wilms tumor 1 (WT1), transcript variant B, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
$261.00
In Stock*
Need Bulk or Customize
Customization Options:
  • Bulk quantity
  • Different host
  • Tags
  • Mutations
  • Buffers
  • SEC testing
  • Concentration
Proudly made in the USA
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length WT1
Tag N-His
Predicted MW 55.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_077742
Locus ID 7490
UniProt ID P19544
Cytogenetics 11p13
RefSeq Size 3020
RefSeq ORF 1542
Synonyms AWT1; GUD; NPHS4; WAGR; WIT-2; WT33
Summary This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Mar 2015]
Protein Families Druggable Genome, Transcription Factors
Write Your Own Review
You're reviewing:Wilms Tumor Protein (WT1) (NM_024424) Human Recombinant Protein
Your Rating
SKU Description Size Price
LC411289 WT1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC424762 WT1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC434129 WT1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$134.00
LY411289 Transient overexpression lysate of Wilms tumor 1 (WT1), transcript variant C 100 ug
$665.00
LY424762 Transient overexpression lysate of Wilms tumor 1 (WT1), transcript variant A 100 ug
$665.00
LY434129 Transient overexpression lysate of Wilms tumor 1 (WT1), transcript variant F 100 ug
$436.00
TP760989 Purified recombinant protein of Human Wilms tumor 1 (WT1), transcript variant A, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
$261.00
TP762366 Purified recombinant protein of Human Wilms tumor 1 (WT1), transcript variant B, Met1-Ala78-GGGGS-Lys141-Gly229, with N-terminal His tag, expressed in E.coli, 50ug 50 ug
$249.00

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.