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GABARAPL2 (NM_007285) Human Recombinant Protein

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SKU
TP760641
Purified recombinant protein of Human GABA(A) receptor-associated protein-like 2 (GABARAPL2), with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length GABARAPL2
Tag N-His
Predicted MW 13.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_009216
Locus ID 11345
UniProt ID P60520
Cytogenetics 16q23.1
RefSeq Size 450
RefSeq ORF 351
Synonyms ATG8; ATG8C; GATE-16; GATE16; GEF-2; GEF2
Summary Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
Protein Pathways Regulation of autophagy
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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