MSL2L1 (MSL2) (NM_018133) Human Recombinant Protein

SKU
TP760587
Purified recombinant protein of Human male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length MSL2
Tag N-His
Predicted MW 62.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_060603
Locus ID 55167
UniProt ID Q9HCI7
Cytogenetics 3q22.3
RefSeq Size 4696
RefSeq ORF 1731
Synonyms MSL-2; MSL2L1; RNF184
Summary Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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Other "MSL2L1" proteins (4)
SKU Description Size Price
LC413286 Lyophilized MSL2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC428876 Lyophilized MSL2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY413286 Transient overexpression lysate of male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY428876 Transient overexpression lysate of male-specific lethal 2 homolog (Drosophila) (MSL2), transcript variant 2 (as WB positive control) 100 ug
$436.00

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