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PRCP (NM_005040) Human Recombinant Protein

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SKU
TP760531
Purified recombinant protein of Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 1, with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length PRCP
Tag N-His
Predicted MW 53.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_005031
Locus ID 5547
UniProt ID P42785
Cytogenetics 11q14.1
RefSeq Size 2161
RefSeq ORF 1488
Synonyms HUMPCP; PCP
Summary This gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. A pseudogene of this gene has been identified on chromosome 2. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. provided by RefSeq, Jan 2016
Protein Categories Enzyme: Peptidases, Intracellular Proteins
Protein Families Druggable Genome, Protease, Transmembrane
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Other "PRCP" proteins (4)
SKU Description Size Price
LC403704 Lyophilized PRCP HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC417565 Lyophilized PRCP HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403704 Transient overexpression lysate of prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY417565 Transient overexpression lysate of prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 1 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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