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FBXO44 (NM_033182) Human Recombinant Protein

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SKU
TP760409
Purified recombinant protein of Human F-box protein 44 (FBXO44), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length FBXO44
Tag N-His
Predicted MW 29.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_149438
Locus ID 93611
UniProt ID Q9H4M3
Cytogenetics 1p36.22
RefSeq Size 2948
RefSeq ORF 765
Synonyms FBG3; FBX6A; FBX30; Fbx44; Fbxo6a
Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Several alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. provided by RefSeq, Feb 2015
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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Other "FBXO44" proteins (10)
SKU Description Size Price
PH319237 FBXO44 MS Standard C13 and N15-labeled recombinant protein (NP_904320) 10 ug
$3,360.00
LC403232 Lyophilized FBXO44 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC405197 Lyophilized FBXO44 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC405198 Lyophilized FBXO44 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423077 Lyophilized FBXO44 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403232 Transient overexpression lysate of F-box protein 44 (FBXO44), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY405197 Transient overexpression lysate of F-box protein 44 (FBXO44), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY405198 Transient overexpression lysate of F-box protein 44 (FBXO44), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY423077 Transient overexpression lysate of F-box protein 44 (FBXO44), transcript variant 4 (as WB positive control) 100 ug
$436.00
TP319237 Recombinant protein of human F-box protein 44 (FBXO44), transcript variant 3, 20 µg 20 ug
$867.00

file-alt Citations

FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
Shen, Qiu, Wu et al
Cell (2020) 184 (2), 352-369.e23 DOI: 10.1016/j.cell.2020.11.042
Cited by 116
AI Summary: OriGene’s recombinant FBXO44 protein (Cat# TP760409) was used in this study to investigate the role of FBXO44 in silencing repetitive elements in cancer cells.
Snippet: Skip to article;Chemicals, peptides, and recombinant proteins Proteinase K Thermo Fisher Scientific Cat# AM2546 Streptavidin beads Cell Signaling Cat# 3419 Protein G agarose Millipore Cat# 16-266 3x FLAG Peptide Sigma-Aldrich Cat# F4799 Recombinant FBXO44 protein OriGene Cat# TP760409 Synthetic biotinylated nucleosomes EpiCypher Cat# 16-0006;16-0325
Showing 1-1 of 1 papers.
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