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Endothelin 3 (EDN3) (NM_000114) Human Recombinant Protein

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SKU
TP760408
Purified recombinant protein of Human endothelin 3 (EDN3), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length EDN3
Tag N-His
Predicted MW 22.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000105
Locus ID 1908
UniProt ID P14138
Cytogenetics 20q13.32
RefSeq Size 2438
RefSeq ORF 714
Synonyms ET-3; ET3; HSCR4; PPET3; WS4B
Summary The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Oct 2014
Protein Families Druggable Genome, Secreted Protein
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Other "Endothelin 3" proteins (5)
SKU Description Size Price
LC400036 Lyophilized EDN3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC404139 Lyophilized EDN3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400036 Transient overexpression lysate of endothelin 3 (EDN3), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY404139 Transient overexpression lysate of endothelin 3 (EDN3), transcript variant 4 (as WB positive control) 100 ug
$436.00
TP761588 Purified recombinant protein of Human endothelin 3 (EDN3), transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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