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c Fos (FOS) (NM_005252) Human Recombinant Protein

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SKU
TP760257
Recombinant protein of human FBJ murine osteosarcoma viral oncogene homolog (FOS), with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
4 Weeks*
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Frequently Bought Together (1)

TA806977 FOS mouse monoclonal antibody, clone OTI7D6 (formerly 7D6) 100 ul
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length FOS
Tag N-His
Predicted MW 40.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_005243
Locus ID 2353
UniProt ID P01100
Cytogenetics 14q24.3
RefSeq Size 2158
RefSeq ORF 1140
Synonyms AP-1; C-FOS; p55
Summary The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. provided by RefSeq, Jul 2008
Protein Categories Cytokines, Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Transcription Factors
Protein Pathways B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway
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Other "c Fos" proteins (3)
SKU Description Size Price
LC401614 Lyophilized FOS HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401614 Transient overexpression lysate of FBJ murine osteosarcoma viral oncogene homolog (FOS) (as WB positive control) 100 ug
$436.00
TP761815 Purified recombinant protein of uman FBJ murine osteosarcoma viral oncogene homolog (FOS), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug 50 ug
$270.00

file-alt Citations

Epigenetic memory of colitis promotes tumour growth
Nagaraja, Ojeda-Miron, Zhang et al
Nature (2026)
Cited by 28
AI Summary: In this study, OriGene’s recombinant FOS (TP760257), FOXP1 (TP313862), and FOXA1 (TP306045) proteins were used in in vitro assays to investigate how specific transcription factors contribute to the epigenetic memory of colitis in colonic stem cells.
Snippet: with the following modifications: briefly, selected sequences (25 ng per reaction) were incubated with various combinations of recombinant JUN (Active Motif, 31116), FOS (OriGene, TP760257), FOXP1 (OriGene, TP313862) and FOXA1 protein (OriGene, TP306045)
Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33
Connelly, Hullin, Abdolalizadeh et al
Nat Commun (2025) 16 (1), 4055 DOI: 10.1038/s41467-025-59109-2
Cited by 2
AI Summary: OriGene products contributed to this study by providing recombinant proteins—ELF2 (TP760288), ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), and FOS2L (TP760114)—used in functional assays to investigate gene regulatory mechanisms underlying pancreatic cancer risk.
Snippet: ELF2 (TP760288), ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), FOS2L (TP760114) proteins were purchased from Origene (Rockville, MD). c-JUN was purchased from Abcam (Waltham, MA) (ab84134). ELF5, which has negligible expression in the pancreas, was not tested
FigureFigureFigure
Allelic effects on KLHL17 expression likely mediated by JunB/D underlie a PDAC GWAS signal at chr1p36.33
Connelly, Hullin, Abdolalizadeh et al
medRxiv (2024)
Snippet: ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), FOS2L (TP760114) protein were purchased from Origene (Rockville, MD). c-JUN was purchased from Abcam (Waltham, MA) (ab84134). ELF5, which has negligible expression in the pancreas, was not tested
FigureFigureFigure
Showing 1-3 of 3 papers.
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