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Ephrin A1 (EFNA1) (NM_182685) Human Recombinant Protein

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SKU
TP760225
Recombinant protein of human ephrin-A1 (EFNA1), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length EFNA1
Tag N-His
Predicted MW 19.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_872626
Locus ID 1942
UniProt ID P20827
Cytogenetics 1q22
RefSeq Size 1524
RefSeq ORF 549
Synonyms B61; ECKLG; EFL1; EPLG1; GMAN; LERK-1; LERK1; TNFAIP4
Summary This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. provided by RefSeq, Jul 2008
Protein Categories Secreated Proteins
Protein Families Druggable Genome
Protein Pathways Axon guidance
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Documents
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Other "Ephrin A1" proteins (7)
SKU Description Size Price
PH310635 EFNA1 MS Standard C13 and N15-labeled recombinant protein (NP_004419) 10 ug
$3,360.00
LC401408 Lyophilized EFNA1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC405448 Lyophilized EFNA1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401408 Transient overexpression lysate of ephrin-A1 (EFNA1), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY405448 Transient overexpression lysate of ephrin-A1 (EFNA1), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP310635 Recombinant protein of human ephrin-A1 (EFNA1), transcript variant 1, 20 µg 20 ug
$867.00
TP720763 Purified recombinant protein of Human ephrin-A1 (EFNA1), transcript variant 1 10 ug
$275.00

file-alt Citations

The Human Blood-Brain Barrier Internalizes Cryptococcus neoformans via the EphA2-Tyrosine Kinase Receptor
Aaron, Jamklang, Uhrig et al
Cell. Microbiol. (2017)
AI Summary: OriGene’s recombinant human ephrinA1 was used in this study to investigate how activation of the EphA2 signaling pathway influences the ability of Cryptococcus neoformans to cross the human blood-brain barrier.
Snippet: All rights reserved. purchased from Sigma Aldrich. Recombinant human ephrinA1 was purchased from Origene. The in vitro blood-brain barrier (BBB) model and transcytosis assay The in vitro static monolayer model of the human BBB consisted of a transwell
Showing 1-1 of 1 papers.
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