IHO1 (NM_178173) Human Recombinant Protein

SKU
TP760152
Recombinant protein of human coiled-coil domain containing 36 (CCDC36), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length CCDC36
Tag N-His
Predicted MW 65.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_835467
Locus ID 339834
UniProt ID Q8IYA8
Cytogenetics 3p21.31
RefSeq Size 2994
RefSeq ORF 1752
Synonyms CCDC36; CT74; LELA1
Summary Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
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Other "IHO1" proteins (2)
SKU Description Size Price
LC406013 Lyophilized CCDC36 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY406013 Transient overexpression lysate of coiled-coil domain containing 36 (CCDC36), transcript variant 1 (as WB positive control) 100 ug
$436.00

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