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PATZ1 (NM_032051) Human Recombinant Protein

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SKU
TP760139
Recombinant protein of human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 4, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length PATZ1
Tag N-His
Predicted MW 57.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_114440
Locus ID 23598
UniProt ID Q9HBE1
Cytogenetics 22q12.2
RefSeq Size 3021
RefSeq ORF 1611
Synonyms dJ400N23; MAZR; PATZ; RIAZ; ZBTB19; ZNF278; ZSG
Summary The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Transcription Factors
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Other "PATZ1" proteins (5)
SKU Description Size Price
LC410365 Lyophilized PATZ1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC415364 Lyophilized PATZ1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY410365 Transient overexpression lysate of POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 4 (as WB positive control) 100 ug
$436.00
LY415364 Transient overexpression lysate of POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 1 (as WB positive control) 100 ug
$665.00
TP760945 Purified recombinant protein of Human POZ (BTB) and AT hook containing zinc finger 1 (PATZ1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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