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FRA2 (FOSL2) (NM_005253) Human Recombinant Protein

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SKU
TP760114
Recombinant protein of human FOS-like antigen 2 (FOSL2), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length FOSL2
Tag N-His
Predicted MW 35.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_005244
Locus ID 2355
UniProt ID P15408
Cytogenetics 2p23.2
RefSeq Size 4015
RefSeq ORF 978
Synonyms FRA2
Summary The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. provided by RefSeq, Jul 2014
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Transcription Factors
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Documents
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Other "FRA2" proteins (2)
SKU Description Size Price
LC417421 Lyophilized FOSL2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY417421 Transient overexpression lysate of FOS-like antigen 2 (FOSL2) (as WB positive control) 100 ug
$436.00

file-alt Citations

Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33
Connelly, Hullin, Abdolalizadeh et al
Nat Commun (2025) 16 (1), 4055 DOI: 10.1038/s41467-025-59109-2
Cited by 2
AI Summary: OriGene products contributed to this study by providing recombinant proteins—ELF2 (TP760288), ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), and FOS2L (TP760114)—used in functional assays to investigate gene regulatory mechanisms underlying pancreatic cancer risk.
Snippet: ELF2 (TP760288), ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), FOS2L (TP760114) proteins were purchased from Origene (Rockville, MD). c-JUN was purchased from Abcam (Waltham, MA) (ab84134). ELF5, which has negligible expression in the pancreas, was not tested
FigureFigureFigure
Allelic effects on KLHL17 expression likely mediated by JunB/D underlie a PDAC GWAS signal at chr1p36.33
Connelly, Hullin, Abdolalizadeh et al
medRxiv (2024)
Snippet: ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), FOS2L (TP760114) protein were purchased from Origene (Rockville, MD). c-JUN was purchased from Abcam (Waltham, MA) (ab84134). ELF5, which has negligible expression in the pancreas, was not tested
FigureFigureFigure
Showing 1-2 of 2 papers.
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