ZC3H8 (NM_032494) Human Recombinant Protein

SKU
TP760094
Recombinant protein of human zinc finger CCCH-type containing 8 (ZC3H8), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length ZC3H8
Tag N-His
Predicted MW 33.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_115883
Locus ID 84524
UniProt ID Q8N5P1
Cytogenetics 2q14.1
RefSeq Size 1609
RefSeq ORF 891
Synonyms Fliz1; ZC3HDC8
Summary Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins, Transciption Factors
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Other "ZC3H8" proteins (2)
SKU Description Size Price
LC410072 Lyophilized ZC3H8 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY410072 Transient overexpression lysate of zinc finger CCCH-type containing 8 (ZC3H8) (as WB positive control) 100 ug
$436.00

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