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Mitofilin (IMMT) (NM_006839) Human Recombinant Protein

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SKU
TP760022
Recombinant protein of human inner membrane protein, mitochondrial (IMMT), nuclear gene encoding mitochondrial protein, transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Size:
50 ug
  $270.00
In Stock*
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Frequently Bought Together (1)

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length IMMT
Tag N-His
Predicted MW 83.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 100 mM arginine, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_006830
Locus ID 10989
UniProt ID Q16891
Cytogenetics 2
RefSeq Size 3018
RefSeq ORF 2274
Synonyms HMP; Mic60; MICOS60; MINOS2; P87; P87/89; P89; PIG4; PIG52
Summary Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
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Other "Mitofilin" proteins (2)
SKU Description Size Price
LC416384 Lyophilized IMMT HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416384 Transient overexpression lysate of inner membrane protein, mitochondrial (mitofilin) (IMMT), nuclear gene encoding mitochondrial protein, transcript variant 1 (as WB positive control) 100 ug
$436.00

file-alt Citations

Mitochondrial DNA variation in Alzheimer's disease reveals a unique microprotein called SHMOOSE
Miller, Kim, Mehta et al
Mol Psychiatry (2022)
Cited by 57
AI Summary: OriGene’s recombinant mitofilin protein (TP760022) was used in reciprocal dot blot experiments to study the interaction between SHMOOSE microprotein variants and mitofilin, helping to elucidate SHMOOSE’s mitochondrial localization and function in Alzheimer’s disease research.
Snippet: Mitochondrial DNA variants have previously associated with disease, but the underlying mechanisms have been largely elusive. Here, we report that mitochondrial SNP Save;Third, we conducted reciprocal dot blots for SHMOOSE, SHMOOSE.D47N, and mitofilin by immobilizing 140 ng of recombinant mitofilin (OriGene TP760022), SHMOOSE, or SHMOOSE.D47N on nitrocellulose membranes. …
Showing 1-1 of 1 papers.
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