RPGR (NM_000328) Human Recombinant Protein

SKU
TP750193
Purified recombinant protein of Human retinitis pigmentosa GTPase regulator (RPGR), transcript variant A, full length, with N-terminal His tag, expressed in E.coli, 50ug
  $380.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the full-length of RPGR
Tag N-His
Predicted MW 90.1 kDa
Concentration >0.05 µg/µL as determined by Bradford protein assay method.
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 250 mM NaCl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000319
Locus ID 6103
UniProt ID Q92834
Cytogenetics Xp11.4
RefSeq Size 3082
RefSeq ORF 2445
Synonyms COD1; CORDX1; CRD; orf15; PCDX; RP3; RP15; XLRP3
Summary This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. provided by RefSeq, Dec 2008
Protein Categories Intracellular Proteins, Membrane Proteins, Nervous system Diseases
Protein Families Druggable Genome
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Other "RPGR" proteins (2)
SKU Description Size Price
LC424796 Lyophilized RPGR HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY424796 Transient overexpression lysate of retinitis pigmentosa GTPase regulator (RPGR), transcript variant A (as WB positive control) 100 ug
$665.00

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