Oncostatin M (OSM) (NM_020530) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | Tag Free |
| Predicted MW | 28.6 kDa |
| Concentration | Resuspend the protein to the desired concentration in proper buffer. |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Lyophilized from a sterile solution containing 20 mM PB, pH 7.4 |
| Endotoxin | < 0.1 EU per 1 µg of the protein by the LAL |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NP_065391 |
| Locus ID | 5008 |
| UniProt ID | P13725 |
| Cytogenetics | 22q12.2 |
| RefSeq Size | 1869 |
| RefSeq ORF | 756 |
| Summary | This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. provided by RefSeq, Jan 2016 |
| Protein Categories | Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway |
| Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Oncostatin M" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH304277 | OSM MS Standard C13 and N15-labeled recombinant protein (NP_065391) | 10 ug |
$3,360.00
|
|
| LC412433 | Lyophilized OSM HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY412433 | Transient overexpression lysate of oncostatin M (OSM) (as WB positive control) | 100 ug |
$436.00
|
|
| TP304277 | Recombinant protein of human oncostatin M (OSM), 20 µg | 20 ug |
$867.00
|
|
| TP720609 | Purified recombinant protein of Human oncostatin M (OSM) | 10 ug |
$340.00
|
|
Citations
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