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Il34 (NM_001135100) Mouse Recombinant Protein

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SKU
TP723760
Purified recombinant protein of Mouse interleukin 34 (Il34), transcript variant 1
Size:
10 ug
  $625.00
5 Days*
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Specifications
Specifications
Product Data
Species Mouse
Expression Host CHO
Expression cDNA Clone or AA Sequence
Protein Sequence
Mouse IL-34, the region of Met1- Pro235, from gene Accession# NM_001135100.1
Tag C-His
Predicted MW 26 kDa
Concentration lot specific
Purity >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 10 mM NaH2PO4, 0.5 M NaCl, pH 7.4
Bioactivity The ED50 is 20 - 30 ng/ml, corresponding to a specific activity of 3.3 - 5 x 10^4 units/mg, determined by M-NFS-60 cell proliferation induction in a dose dependent manner.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001128572
Locus ID 76527
UniProt ID Q8R1R4
Cytogenetics 8 E1
RefSeq Size 1747
RefSeq ORF 705
Synonyms 2010004A03Rik; AI593503
Summary Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1 (By similarity).UniProtKB/Swiss-Prot Function
Protein Categories Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins
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Other "Il34" proteins (1)
SKU Description Size Price
TP502857 Purified recombinant protein of Mouse interleukin 34 (Il34), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug 20 ug
$1,020.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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