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FCGR1A Human Recombinant Protein

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SKU
TP721253
APC Conjugated Human CD64 Protein (C-His)
Size:
25 ug 100 ug
  $430.00
5 Days*
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Frequently Bought Together (1)

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Specifications
Specifications
Product Data
Species Human
Expression Host CHO
Expression cDNA Clone or AA Sequence
Protein Sequence
Gln16-Thr287
Tag C-His
Predicted MW The protein has the predicted molecular weight of 32kDa and migrates at approximately 50-60 kDa on SDS-PAGE with DTT-reduced condition before APC conjugatoin.
Concentration 25µg size is bottled at 0.1mg/mL concentration. 100 µg size is bottled at lot specific concentration.
Purity >90%
Conjugation APC
Presentation State Purified
Buffer 1xPBS buffer, pH7.4, 0.09% NaN3 with a carrier protein
Bioactivity Positive

The definition of the active protein (purified and biotinylated) is defined as the protein that can bind to its biological receptor/ligand. For conjugated protein, it is defined with its function to bind to the ScFv of the active CAR-transfected cells in flow cytometry test.
Preparation Affinity Ni-NTA
Recommended Dilution FACS
Storage An unopened vial can be stored at 4°C for 2 weeks or at -20°C and below for six months. This stock solution should be aliquoted and stored at ≤ -70°C to minimize the freeze/thaw cycles.
Stability 6 Months
Shipping Blue Ice
Reference Data
RefSeq NP_000557.1
Locus ID 2209
UniProt ID P12314
Summary Receptors for the Fc portion of human IgG (Fc gamma receptors) can be divided into three classes as Fc gamma RI (CD64), RII (CD32), and RIII (CD16). Each of these proteins may be coded by multiple genes and exist in different isoforms. Fc gamma RI or CD64 proteins can bind Fc portion of human IgG with high affinity and play important role in early immune response. In contrast CD16 and CD32 bind human IgG with low affinity and can only recognize the IgG aggregates with multivalent antigens. Human CD64 is expressed constitutively on macrophages and monocytes and its expression can be induced by IFNg or G-CSF on polymorphonuclear leukocytes.
Protein Families FACS
Protein Pathways Fc gamma R-mediated phagocytosis, Hematopoietic cell lineage, Systemic lupus erythematosus
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Other "CD64" proteins (6)
SKU Description Size Price
LC400193 Lyophilized FCGR1A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400193 Transient overexpression lysate of Fc fragment of IgG, high affinity Ia, receptor (CD64) (FCGR1A) (as WB positive control) 100 ug
$436.00
TP721250 Human CD64 Protein (C-His-Avi) 25 ug
$300.00
TP721251 Biotinylated Human CD64 Protein (C-His-Avi) 25 ug
$430.00
TP721252 PE Conjugated Human CD64 Protein (C-His) 25 ug
$430.00
TP762370 Purified recombinant protein of Human Fc fragment of IgG, high affinity Ia, receptor (CD64) (FCGR1A), Gln16-His292, with N-terminal His tag, expressed in E.coli, 50ug 50 ug
$260.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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