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ARMET (MANF) (NM_006010) Human Recombinant Protein

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SKU
TP721225
Purified recombinant protein of Human mesencephalic astrocyte-derived neurotrophic factor (MANF)
Size:
10 ug 500 ug 50 ug 1 mg
  $275.00
7 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Asp20-Tyr337
Tag C-His
Predicted MW 19.2 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_006001
Locus ID 7873
UniProt ID P55145
Cytogenetics 3p21.2
RefSeq Size 993
RefSeq ORF 555
Synonyms ARMET; ARP
Summary The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. provided by RefSeq, Apr 2014
Protein Categories Growth Factors, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
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Other "ARMET" proteins (4)
SKU Description Size Price
PH321555 MANF MS Standard C13 and N15-labeled recombinant protein (NP_006001) 10 ug
$3,360.00
LC401818 Lyophilized MANF HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401818 Transient overexpression lysate of mesencephalic astrocyte-derived neurotrophic factor (MANF) (as WB positive control) 100 ug
$436.00
TP321555 Recombinant protein of human arginine-rich, mutated in early stage tumors (ARMET), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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