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Activin Receptor Type IIA (ACVR2A) (NM_001616) Human Recombinant Protein

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SKU
TP721059
Purified recombinant protein of Human activin A receptor, type IIA (ACVR2A)
Size:
10 ug 500 ug 50 ug 1 mg
  $190.00
7 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Ala20-Pro134
Tag C-Fc&His
Predicted MW 41.2 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_001607
Locus ID 92
UniProt ID P27037
Cytogenetics 2q22.3-q23.1
RefSeq Size 5244
RefSeq ORF 1539
Synonyms ACTRII; ACVR2
Summary This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. provided by RefSeq, Jun 2013
Protein Categories Enzyme: Kinases, Growth Factors, Membrane Proteins
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway
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Other "Activin Receptor Type IIA" proteins (3)
SKU Description Size Price
LC419844 Lyophilized ACVR2A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419844 Transient overexpression lysate of activin A receptor, type IIA (ACVR2A) (as WB positive control) 100 ug
$436.00
TP720687 Purified recombinant protein of Human activin A receptor, type IIA (ACVR2A) 10 ug
$220.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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