UCMA (NM_145314) Human Recombinant Protein

CAT#: TP721011

Purified recombinant protein of Human upper zone of growth plate and cartilage matrix associated (UCMA)

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Ser65-Thr138
• Tag: Tag Free
• Predicted MW: 9.8 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at -80°C.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_660357
• Locus ID: 221044
• UniProt ID: Q8WVF2, A0A067XJX6
• Cytogenetics: 10p13
• Refseq Size: 840
• Refseq ORF: 414
• Synonyms: C10orf49; GRP; GRP/UCMA
• Summary: This gene encodes a chondrocyte-specific, highly charged protein that is abundantly expressed in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the encoded protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the encoded protein is associated with osteoarthritis in humans. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]
• Protein Families: Secreted Protein