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UCMA (NM_145314) Human Recombinant Protein

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SKU
TP721011
Purified recombinant protein of Human upper zone of growth plate and cartilage matrix associated (UCMA)
Size:
10 ug 500 ug 50 ug 1 mg
  $340.00
7 Weeks*
Bulk/Customize

Frequently Bought Together (1)

TA306793 Rabbit Polyclonal UCMA Antibody
100 ug
$640.00

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Ser65-Thr138
Tag Tag Free
Predicted MW 9.8 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of PBS,PH7.2.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_660357
Locus ID 221044
UniProt ID Q8WVF2
Cytogenetics 10p13
RefSeq Size 840
RefSeq ORF 414
Synonyms C10orf49; GRP; GRP/UCMA
Summary This gene encodes a chondrocyte-specific, highly charged protein that is abundantly expressed in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the encoded protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the encoded protein is associated with osteoarthritis in humans. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2015
Protein Categories Secreated Proteins
Protein Families Secreted Protein
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Other "UCMA" proteins (2)
SKU Description Size Price
LC407961 Lyophilized UCMA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY407961 Transient overexpression lysate of upper zone of growth plate and cartilage matrix associated (UCMA) (as WB positive control) 100 ug
$436.00

file-alt Citations

In vivo protective effects of UCMA against cartilage degeneration in monosodium iodoacetate-induced osteoarthritis model
Okuyan, Terzi, Karaboga et al
Can. J. Physiol. Pharmacol. (2020)
Cited by 10
AI Summary: OriGene’s UCMA protein (UCMA, OriGene Technologies Inc, USA) was used for intra-articular injections in rats to assess its protective effects against cartilage degeneration in a monosodium iodoacetate-induced osteoarthritis model.
Snippet: The rats bearing MIA-induced OA were treated with;saline 131 (vehicle group) and 2.5 µg/kg of UCMA (UCMA OriGene Technologies Inc, USA) by intra- 132 articular administration at 2-day intervals for 21 days (in total 7 injections for each rat) and 2
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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