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GCDH (NM_000159) Human Recombinant Protein

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SKU
TP720971
Purified recombinant protein of Human glutaryl-CoA dehydrogenase (GCDH), nuclear gene encoding mitochondrial protein, transcript variant 1
Size:
10 ug 500 ug 50 ug 1 mg
  $275.00
7 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Arg45-Lys438
Tag N-His
Predicted MW 45 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM HEPES, 150mM NaCl, pH 7.4.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_000150
Locus ID 2639
UniProt ID Q92947
Cytogenetics 19p13.13
RefSeq Size 1897
RefSeq ORF 1314
Synonyms ACAD5; GCD
Summary The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. provided by RefSeq, Mar 2013
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Fatty acid metabolism, Lysine degradation, Metabolic pathways, Tryptophan metabolism
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Other "GCDH" proteins (8)
SKU Description Size Price
PH300473 GCDH MS Standard C13 and N15-labeled recombinant protein (NP_000150) 10 ug
$3,360.00
LC415563 Lyophilized GCDH HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC424891 Lyophilized GCDH HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC429397 Lyophilized GCDH HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415563 Transient overexpression lysate of glutaryl-Coenzyme A dehydrogenase (GCDH), nuclear gene encoding mitochondrial protein, transcript variant 2 (as WB positive control) 100 ug
$665.00
LY424891 Transient overexpression lysate of glutaryl-Coenzyme A dehydrogenase (GCDH), nuclear gene encoding mitochondrial protein, transcript variant 1 (as WB positive control) 100 ug
$436.00
LY429397 Transient overexpression lysate of glutaryl-Coenzyme A dehydrogenase (GCDH), nuclear gene encoding mitochondrial protein, transcript variant 2 (as WB positive control) 100 ug
$436.00
TP300473 Recombinant protein of human glutaryl-Coenzyme A dehydrogenase (GCDH), nuclear gene encoding mitochondrial protein, transcript variant 1, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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