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MICA (NM_000247) Human Recombinant Protein

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SKU
TP720672
Purified recombinant protein of Human MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*001)
Size:
10 ug 500 ug 50 ug 1 mg
  $220.00
7 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Glu24-Gln308
Tag C-His
Predicted MW 33.87 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_000238
Locus ID 100507436
UniProt ID Q29983
Cytogenetics 6p21.33
RefSeq Size 1410
RefSeq ORF 1149
Synonyms MIC-A; PERB11.1
Summary This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, Jan 2014
Protein Categories Intracellular Proteins, Membrane Proteins
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Other "MICA" proteins (8)
SKU Description Size Price
PH304447 MICA MS Standard C13 and N15-labeled recombinant protein (NP_000238) 10 ug
$3,360.00
LC400095 Lyophilized MICA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC432900 Lyophilized MICA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400095 Transient overexpression lysate of MHC class I polypeptide-related sequence A (MICA) (as WB positive control) 100 ug
$436.00
LY432900 Transient overexpression lysate of MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*00801) (as WB positive control) 100 ug
$436.00
TP304447 Recombinant protein of human MHC class I polypeptide-related sequence A (MICA), 20 µg 20 ug
$737.00
TP329900 Purified recombinant protein of Homo sapiens MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*00801), 20 µg 20 ug
$737.00
TP720954 Purified recombinant protein of Human MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*001) 10 ug
$260.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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