Lactate Dehydrogenase B (LDHB) (NM_001174097) Human Recombinant Protein

SKU
TP720210M
Recombinant protein of human lactate dehydrogenase B (LDHB), transcript variant 2.
  $785.00
7 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Met1-Leu334
Tag N-His
Predicted MW 38.8 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001167568
Locus ID 3945
UniProt ID P07195
Cytogenetics 12p12.1
Synonyms HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5
Summary This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. provided by RefSeq, Feb 2016
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Cysteine and methionine metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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